Existence of a colonizing Staphylococcus aureus strain isolated in diabetic foot ulcers 1
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چکیده
Existence of a colonizing Staphylococcus aureus strain isolated in diabetic foot ulcers 1 Nourreddine Messad, Tomasz K. Prajsnar, Gerard Lina, David O’Callaghan, Simon J. Foster, 2 Steve A. Renshaw, Eric P. Skaar, Michèle Bes, Catherine Dunyach-Remy, François Vandenesch, 3 Albert Sotto, Jean-Philippe Lavigne* 4 5 National Institute of Health and Medical Research, U1047, University of Montpellier, Faculty of Medicine, 6 30908 Nîmes cedex 02, France 7 MRC Centre for Developmental and Biomedical Genetics, University of Sheffield, Western Bank, Sheffield, 8 S10 2TN, United Kingdom 9 Krebs Institute, University of Sheffield, Western Bank, Sheffield S10 2TN, United Kingdom 10 CIRI, International Center for Infectiology Research, LabEx Ecofect, University of Lyon1, Inserm U1111, 11 Ecole Normale Supérieure de Lyon, CNRS UMR5308, 69008 Lyon, France 12 University Hospital Lyon, Referent National Center of Staphylococcus, Center of Biology and Pathology East, 13 69677 Bron cedex, France 14 Department of Pathology, Microbiology and Immunology, Vanderbilt University School of Medicine, 15 Nashville, Tennessee, United States 16 7 Department of Microbiology, University Hospital Carémeau, 30029 Nîmes cedex 09, France 17 8 Department of Infectious Diseases, University Hospital Carémeau, 30029 Nîmes cedex 09, France 18 19 Correspondence and reprint request to Jean-Philippe Lavigne, Institut National de la Santé et de la 20 Recherche Médicale, U1047, Université de Montpellier, UFR de Médecine, 186 Chemin du Carreau de Lanes, 21 CS 83021, 30908 Nîmes cedex 02, France. E-mail: [email protected] 22 Word count:1976; Number of Tables:2 and Figures:2 23 Running title: Diabetic foot and Staphylococcus aureus 24 25 *
منابع مشابه
Existence of a Colonizing Staphylococcus aureus Strain Isolated in Diabetic Foot Ulcers
Staphylococcus aureus is an opportunistic bacterium capable of causing a wide range of severe diseases when it gains access to underlying tissues. Paradoxically, S. aureus is a common inhabitant of the skin microflora and colonizes the nares and other human mucosa. The purpose of this study was to determine the genetic basis for the differences in the pathogenic versus colonizing potential of S...
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